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CEO Corner2021-02-22T15:55:45+00:00

See how our technology creates Endless Possibilities

CEO Corner

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Nanoplasmid™ could be used to improve 50% of all vectors used in gene therapy trials, including AAV, Lentivirus, Retrovirus and Plasmid DNA.

#genetherapy #vectors

HyperGRO™ fermentation is NTCs high-efficiency process for growing plasmids. The HyperGRO™ media and high cell density fed-batch fermentation process is capable of producing very high yields (> 2 gram/L) of high-quality plasmid DNA in Escherichia coli.

Increased transgene expression and tunable innate immunity activation for gene therapy or vaccination applications – Nanoplasmid™ makes it possible.

This translates to much lower observed toxicity and vector inactivation during cell transfection.

The safety concern with marker gene transfer can be eliminated by retrofit of the vector backbone encoded bacterial selection marker to an antibiotic free, non-protein-based selection gene.
We developed an optimized antisense RNA based antibiotic-free selection vector backbone.

The Nanoplasmid™ can be used for multiple applications providing endless possibilities.
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