Biologics by design
Nanoplasmids™ and Manufacturing
A dramatically improved Key Cassette (<500 bp) that is designed to replace antiquated bacterial backbones that have for decades been the industry standard in DNA vectors. It is perfect for gene and cell therapeutics, DNA vaccines, immunotherapeutics, and for improving the performance and titers of existing viral and transposon vectors. Easily fermentable in E. coli, there are no downstream modifications or antibiotics required.
The Nanoplasmid™ platform outperforms other systems. This gives our partners a competitive edge and, by relying on a virtual team at NTC, helps them concentrate on what is most important: advancing rapidly through preclinical and clinical testing of their genes of choice.
HyperGRO™ Fermentation Process: Record Yields for Plasmid DNA Production
NTC’s HyperGRO™ fermentation process and media are used routinely for production of gene therapy vectors and DNA vaccines. Improvements in fed-batch fermentation resulted in plasmid DNA yields of >2.2g/L. [Patent Ref: PCT/US05/29238]
NTC scientists are available to assist you with project development.
Assistance with preparing regulatory documents
Basic consulting is included with products and services, whereas problem solving, advanced product design, regulatory writing and tech transfer are available at NTC's listed rates.